Mullins and CTU try and track down Carter, as Andy is forced to do something he doesn't want to do. Rebecca's interrogation techniques lead Donovan to question her judgment. Isaac turns to his friends for help.
After leading a mission to eliminate terrorist leader Sheik Ibrahim Bin-Khalid, Eric Carter, returns to the U.S. and finds out that he and his squad mates are targeted for assassination in retaliation for Bin-Khalid's death. With nowhere else to turn, Carter asks CTU to help him save his life while also stopping one of the largest-scale terror attacks on American soil.
The events will take place three years after the events in 24: Live Another Day and is set in Washington, D.C.