In the aftermath of Eddie's car accident, Katherine leans on their beloved group of friends for support. Meanwhile, Rome and Regina face a tough decision about the future of their family, and Delilah sees how her kids are thriving and wants the same for herself. Maggie jump starts her new life in Oxford, while Gary continues to navigate his new relationship with Darcy.
Katherine and Theo learn to adapt to their new life after Eddie's accident. Rome and Regina grow distant as Rome suppresses his anger over the failed adoption. Delilah struggles with having a date at the house while the kids are away. Maggie unexpectedly bonds with her new roommate as Gary navigates trying to stay friends with her while building his relationship with Darcy.
Katherine discovers a possible connection between Eddie's accident and Alex's mysterious death. Rome seeks help to address some anger issues. Maggie continues on her journey of self-discovery in England. Delilah prepares for her trip.
Eddie's injuries put a strain on his marriage as he secretly continues to manage the pain from the accident. Meanwhile, Rome struggles with his movie and finds an ally in Shanice; and Maggie continues her journey in England as she and Jamie grow closer than ever.
As COVID-19 becomes more widespread across the U.S., Boston goes into lockdown putting Rome's movie in jeopardy and forcing Maggie to return home from Oxford. Because the hospitals are overwhelmed with coronavirus patients, Eddie's back surgery is cancelled, leading him to take desperate measures to cope with the severe pain.
Maggie is forced to face the harsh reality that cancer still controls her life, while Gary must choose between supporting a friend in need and building his relationship with Darcy. Meanwhile, Rome helps Regina at Someday during the COVID-19 transition.
Regina is faced with making difficult changes to keep Someday afloat during the COVID lockdown, while Eddie struggles to keep his secret drug addiction under wraps. Elsewhere, Maggie fears she may have revealed a bit too much on her podcast.
Katherine realizes Theo is being discriminated against when one of his classmates asks him to wear a mask during Zoom school. Meanwhile, Regina finds her Vicodin is missing and suspects that Rome might've been the one to take them.
When Eddie reveals his truth, Katherine suffers the consequences... again. Rome and Regina offer support to Tyrell and his mother, and Maggie and Jamie are forced to address their relationship status.
Sophie is distraught after a disturbing encounter, and Gary calls in Maggie and Regina for support. Meanwhile, Eddie makes an unexpected friend.
Despite her trauma, Sophie goes through with her music school audition but quickly realizes she is struggling to move forward. Meanwhile, Rome and Regina grow closer to Tyrell; Katherine and Eddie are at a crossroads; and Gary reconnects with his father.
Gary's dad connects with Darcy about his personal experience from the Vietnam War. Meanwhile, during a dinner hosted by Rome and Regina, the video of George Floyd's hug is released, and they watch together in shock.
In response to the killing of George Floyd, the group of friends are forced to reevaluate their own racial biases and take to the streets of Boston. Rome opts out in favor of his mental health and has a candid conversation with his father about how to effect change.
Rome tries to help Tyrell find a productive outlet for his frustrations about the racial issues in America while Regina is dealing with her mother's concerns regarding the future of Someday. Meanwhile, Katherine and Eddie struggle to navigate the waters of their relationship.