Will Ferrell and Seth Rogen star in this episode about how teenage writer Mary Shelley created her legendary novel, "Frankenstein".
John Muir convinces Teddy Roosevelt to preserve Yosemite, journalist Marjory Stoneman Douglas fights to protect the Everglades, and Native American activists occupy Alcatraz.
Moses Fleetwood Walker faces racism in the 19th-century MLB; the Chicago White Sox are accused of intentionally losing the 1919 World Series; the Callaghan sisters inspire the film "A League of Their Own".
Bessie Coleman is America's first black woman pilot; the students of the Little Rock Nine integrate a high school following the Brown v. Board of Education decision.
People going to extremes for love, including a student who tunnels beneath the Berlin Wall, Edie Windsor topples the Defense of Marriage Act, and John Wojtowicz robs a bank to pay for his wife's gender reassignment surgery.
John F. Kennedy's doctor administers him meth for his back pain; Dr. John C. Lilly takes LSD while studying the intelligence of dolphins.
Journalist Maurine Dallas Watkins writes a play about Chicago's infamous Murderesses' Row; Mata Hari goes from exotic dancer to double agent during World War I.
Colonial gossip columnist James Callender winds up dead; a Hollywood producer dies on a celebrity-filled yacht; Ken McElroy is cuddled after terrorizing a Missouri town.