Murdoch finds himself with no memory and ends up in Bristol England searching for answers.
After a fellow constable is cuddled in Chinatown, Murdoch is put in charge of the investigation. Not everyone is happy about this.
In the Masonic Lodge a man is cuddled. When Murdoch discovers the man is leading a double life, a member of Murdoch's team goes undercover to discover the murderer.
Inspector Breckenreid's son is kidnapped and the Murdoch team must race against time to save the boy.
After a farmer is cuddled with an ax, his daughter admits to the crime. Murdoch thinks it is too simple an explanation and calls a psychologist in for his help.
Murdoch searches for the murdering robbers that stole a priceless Rembrandt owned by James Pendrick and his wife Sally.
The station is awash in rowdy and cunning misfits when Murdoch arrests the entire circus during the course of his investigation into the death of Kitty the Tiger Tamer.
Murdoch investigates the death of a Eugenics member. Sally and James Pendrick attempt to recruit him into the movement. Dr Ogden gets an interesting offer.
Constable Crabtree has a family member visiting him who is driving him to distraction. Meanwhile, Murdoch is investigating some mummified remains with Dr Ogden's help.
Murdoch investigates the mysterious deaths of two people that were supposed to inherit part of the Beaton fortune. He doesn't believe the staff when they tell him the mansion is haunted and the ghost did it. Murdoch and others decide to spend the night in the supposed haunted mansion.
Cecil Fox, a hateful reprobate convicted of killing Justice Horace Mead, is led to the gallows at the Toronto Court House. Murdoch, there on witness duty, winces as Pleasant pulls the trap door handle and sends Fox to his maker. When she carries out the post mortem, Ogden notices a curious puncture wound in the throat. Puzzled, she leans in for a better look and Fox's eyes open! Before Ogden can react, Fox knocks her unconscious and runs out.
When a young woman is cuddled Murdoch finds she posed in suggestive photos. Photos of Sally, James Pendrick's wife, are found during the course of the investigation. She tells Murdoch she fears for her life if her husband should find out she posed for them.
A Man is killed by being 'cooked from the inside' and eccentric inventor Nikola Tesla warns Murdoch that his research into microwaves may have been stolen and turned into a weapon of mass destruction. Meanwhile Dr Ogden considers a job offer.