When Twilight Sparkle learns about Pinkie Pie's 'Pinkie Sense', her unique ability to sense specific happenings in the immediate future, she is not willing to accept that they are anything but mere coincidences. Twilight decides to, scientifically, find out what's behind Pinkie's ability.
"Get your muzzle out of those books and make some friends!" That's what Princess Celestia tells Twilight Sparkle. She may be the smartest unicorn in Equestria, but Twilight Sparkle gets an "incomplete" in friendship. There's more to life than learning magic, after all - so she goes to Ponyville on a mission to make friends. There she meets five special ponies who take her on exciting adventures and teach her the most powerful magic of all... the magic of friendship!