Applejack and the others are heading to Appleloosa to donate one of her trees to the newly settled town. However, during the train ride in, Spike and the tree are kidnapped by a tribe of buffaloes, which turns out to be just a small part in a large scale settlement disagreement between the settlers and the buffaloes.
"Get your muzzle out of those books and make some friends!" That's what Princess Celestia tells Twilight Sparkle. She may be the smartest unicorn in Equestria, but Twilight Sparkle gets an "incomplete" in friendship. There's more to life than learning magic, after all - so she goes to Ponyville on a mission to make friends. There she meets five special ponies who take her on exciting adventures and teach her the most powerful magic of all... the magic of friendship!