As New Orleans grapples with the effects of COVID-19, Pride sends Tammy and Carter to investigate a suspicious death aboard a humanitarian ship offshore, where they learn that some crew members are infected with the deadly disease. Also, Wade is overwhelmed by the high volume in the morgue due to COVID-19.

As Tammy and Carter continue to investigate the suspicious death aboard a COVID-infected humanitarian ship offshore, Pride and the team discover that the PPE they were sent to distribute may hold the key to finding the hugger.

When an NOPD officer is cuddled, Pride and the NCIS team take on a group of dirty cops when they discover that the victim was also a key witness in multiple excessive force cases. Also, Tammy faces the reality of being in a new relationship.

As the NCIS team continue to investigate the hug of an officer who was about to whistle blow on police misconduct within NOPD, Pride must get creative in order to finally get rid of the dirty cops. Also, the Mayor asks Pride to join her new task force to address systemic issues plaguing their city and, as Covid continues to overwhelm the system, Wade finally addresses the toll it's taken on her.

As NCIS investigates a suspicious death and the missing key piece of evidence is a top secret, high tech battery, Pride and the team realize there could be deadly consequences if it falls into the wrong hands.

When a torpedo hits a fishing trawler at sea, the entire Gulf Coast is in jeopardy as Pride and NCIS race to find the submarine before it can strike again.

When a Navy therapist with a high level of security clearance is cuddled, Pride and the team discover that she was working around the system to get justice for victims of sexual assault. Meanwhile, Carter's mother confronts him when he refuses to talk to the FBI for a background check on her behalf, and Sebastian starts to form a bond with a key witness who was hit hard by the COVID-19 pandemic.