Continuing the journey to Hearthome City, Ash, Dawn, and Brock stop to eat lunch. After eating Turtwig brings them to a cliff where a Hippopotas is stuck on the cliff. After helping it, the Sinnoh Now staff shows up and tells them they were filming it and it accidentally got lost from its family. They decide to help the Pokémon get back to its family, and must do it before Team Rocket captures the easily tricked Pokémon.
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.