Once again Ash sets his sights on a new region and a new adventure. Continuing his journey alone, Ash arrives in the beautiful Unova region with just Pikachu at this side. While on his way to visit Professor Juniper, Unova's resident professor, a mysterious shadow appears above and Pikachu loses the ability to use his electric attacks. Ash also encounters a trainer named Trip and the two decide to have an unlikely ending battle.
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.