With the business of the Red Gyarados over, Ash decides to challenge the Gym Leader Pryce but he isn't in town. They find him meditating under a waterfall. Ash battles him with Phanpy and quickly loses. Afterwards, Pryce tells the gang that his most prized Pokémon Piloswine disappeared a long time ago and he needs help finding it. The group agrees to help and they set out immediately. Jessie and James are nearby and they decide to steal it. Can Ash and the others find it before Jessie and James do?
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.