Frasier has finally moved to Seattle, and is just getting settled in with his new life and radio show. Suddenly things become even more complicated when Niles confronts him about a problem with their dad. Feeling as though it's up to him to help their dad, Frasier allows his father, Martin Crane, to move in with him. Unfortunately for Frasier, he and his dad don't get along too well.
Frasier, still uncomfortable with his new life in Seattle struggles to find some quiet time to read a book.
Frasier and Niles decide to do something special for their dad, and make reservations at a fancy restaurant. When they later find out their reservations were lost, their plans for their dad are foiled, until Martin gives a suggestion. Instead of Niles and Frasier picking a fancy place to eat, Martin tells them to go to one of his old favorites instead. They agree, but results don't end up like they'd hoped.
When Niles points out a column in the News Paper by Derek Mann saying 'I Hate Frasier Crane', Frasier becomes furious. Still infuriated by the remark, Frasier makes some ill comments towards Derek Mann on his radio show. After hearing his coments, Derek Mann calls in and challenges Frasier to a fist fight. Frasier boldly accepts, but everyone knows it won't end well.
Frasier does something for his dad and gets Martin a telescope. Discovering the fun of spying on other people with the telescope, Martin comes accross a lady named Irene. They begin writing each other notes, using the telescopes to read them. Frasier begins to realise his dad has a thing for Irene, and tries to get him to ask her out. But when Martin turns down a date with Irene after their first talk on the telephone and makes up a reason as to why, Frasier decides to find out the real reason.
Frasier purchases a Martha Paxton painting, and at the unveiling of it at his appartment the artist herself attends to witness it...but announces the painting is not done by her and is a fake.
When Frasier advises a caller on his radio show to break up with his girlfriend as Frasier feels that the caller is not treating her right, the woman shows up to confront Frasier about what he did, but they end up dating...then Marco (the caller) comes back into the picture. This leads to Frasier being uncomfortable about breaking his ethics.
When Frasier and Niles see Martin having dinner at a resturaunt with an old friend (Marion), it beings back memories to Frasier and Niles about their childhood when Martin and Esther were arguing a lot, which leads to Frasier and Niles believing that Martin had an affair with Marion.
Frasier gets a new agent, Bulldogs agent, who begins to convince Frasier to start doing commercials on his radio show. Soon after he begins to find himself doing more and more. Finally it comes to a point where he must make a decision that could harm or help his career, do a television commercial dressed as a peanut.
Someone's getting fired at the radio station, and some rumours begin to spread. Frasier learns that it might be Bulldog, and Bulldog over hears him talking about it. Panicking, Bulldog decides to quit his job, and explodes on Ned Miller. When Frasier learns that it wasn't Bulldog who was going to get fired, he feels terrible, and decides to do everything he can to get Bulldogs job back.
Frasier is feeling uncomfortable when a doctor who he took Martin to see who was the same age as Frasier suddenly died. Frasier seeking answers for the cause, goes to the man's shiva to find out.
It's during the Holiday's, and Frasier finds out his son Fredrick isn't coming over for Christmas. With nothing better to do on Christmas day, Frasier decides to air his radio show and ask listeners to give him input of their Holiday Cheer. Unfortunately all the callers are just as depressed as he is, and makes him even more depressed. Still depressed, he ends his show and decides to head down to dine at a local dinner bar, where he is mistaken as a homeless man and discovers how generous other people can be, making it not so bad of a Christmas.
When Frasier mentions that Martin has been sleeping with a woman (Elaine Morris) from the same building they are at, Martin is furious at Frasier for announcing Martin's private life over the radio. This leads the all of Frasier's listeners anxiously waiting to see if Elaine shows up for a date that Frasier tries to set up on his radio show.
When Bulldog and Frasier enter a bachelor auction, Bulldog gets bought by Daphne, Frasier is bought by a model (Kristina) who ends up leaving Frasier for a photoshoot leaving her daughter with Frasier, which leads to Frasier hearing about the terrible way her mother treats her. Frasier distraught by this, confronts Kristina on her return.
After having a conversation with Roz about being ripped off by con-men, Frasier thinks he can tell when someone's a con and when they're not. Later, his dad tells him that it's a lot harder to tell than he thinks, and that he's having three friends coming over for poker, and one's an ex-con. He bets Frasier 20 bucks that he can't guess which one's the ex-con. Like Martin predicted, Frasier got it wrong. He was surprised to find out who the con was, and so was Daphne, as she had made a date with him. Stunned by the news, both Niles and Frasier hurry off to protect Daphne, before something bad happens.
When Frasier learns his ex-wife Lilith is in town for a convention, he invites her over to his place. Shortly after he learns that there is no convention, and that Lilith has other intentions, ones which leave Frasier some what dumbfounded.
Frasier suggest Niles do some sexual role play with Maris, to help strenghten their relationship. When the sexual role play doesn't go as planned, Niles finds himself kicked out of the house, and over at Frasiers. He later calls Maris and they decide to have dinner and make up for what had happened. Daphne offers to prepare the dinner, and both Daphne and Niles find themselves at Maris's house, awaiting her arrivale, but then Niles learns that Maris wont be coming due to a storm. When Frasier finds out Niles and Daphne are all alone together, he hurry's to rescue them, before Niles jepordises his marrige.
Frasier and Roz hope desperately to win a SeaBea (Seattle Radio Awards) this year by bribing the judges with gifts, however a long time nominated but never won radio personality who is retiring after the year is also nominated in the same catagory as Frasier. This leads to Frasier doubting whether he deserves the award if he wins or not.
When Frasier loses Martin's chair...Martin is extremely angry and wants it back. So they go on the hunt to look for it and finally find it at a school play, however the teacher won't give the chair up since its a vital part of the set.
When a twenty year old sales assistant flirts with Frasier, he questions whether a middle-aged man such as himself could find happiness dating her.
When Martin, Frasier, Niles and Daphne take a road trip in a winnebago, everything goes wrong when they end up in another country and Daphne doesn't have a visa to enter the country.
Both Niles and Frasier decide to write a book on psychiatry together. When they find out their deadline for the first few chapters is only a day away, and they haven't even started, they call for desperate measures and decide to lock themselves in a hotel room until at least the first few chapters are complete. Being locked in a hotel room is not an easy task, especially with your brother. As Niles and Frasier begin to argue due to the frusteration of not getting anything done, all hell breaks loose.
When Frasier calls in sick, he has Gil Chesterton fill in for him. When he finds that Gil Chesterton seems to be doing a better job than him, he frantically tries to find someone else, and asks his brother Niles to fill in for him instead. Things go well at first, seeing that Niles isn't as good as he is, but soon Niles begins to pick up the pace. Frasier begins to think that Gil and Niles are trying to take his show, and makes a desperate attempt to get his show back by taking some miracle drugs to help him feel better, which can only mean disaster.
Niles and Frasier end up getting stuck at Café Nervosa when it begins to rain. With nothing better to do, Niles asks Frasier if he's happy, as it's been one year since he had moved to Seattle. Frasier continuously gets interrupted after others continue to barge into their conversation. After everyone else, including Niles leaves, Frasier realises he is happy, and his move to Seattle hasn't been that bad after all.