The death of a teenager is investigated by Brenda and Co. Their search uncovers that the teen may have been part of a plot in which hundreds of people may have been killed by a bomb. Now it is a search against time to find the bomb.
The LAPD has created a new division - Priority Homicide - to deal with high-profile murders and incidents. However, the assistant chief gives the job to a former FBI interrogator (and former lover), Brenda Leigh Johnson, raising ire in Capt. Taylor, the man who thought he would be getting the job... and the second highest rank in the department.
Brenda proves to be a contradiction in terms. She is socially absentminded at times; she has an addiction to junk food; her quirks can be annoying; and she can be a spitfire when the time calls for it. But, to the surprise of her team, she is also very adept, sharp, observant, and is a "closer" - someone who can get the confessions and the convictions.