Red continues to battle Berlin and faces a new threat from a man named Lord Baltimore. An important person comes back from the past into Red's world. Meanwhile, Liz tries to move forward with her life after her showdown with Tom.
A robbery provides Red with an opportunity to take down a questionable bank. Liz questions Red's intentions during the course of her investigation. An impressive addition is made to Cooper's team.
When a body is found missing a heart, Keen and Ressler join forces with Samar Navabi to investigate Dr. Covington's operation; Red and an associate try to take advantage of an opportunity in Indonesia.
Several nonunhappy citizens all of a sudden become huggers, prompting Red to think a dangerous socio-psychological experiment may be taking place. Naomi and her husband are given a complicated proposition.
The team targets an eco-terrorist cell seeking a deadly weapon. Liz attempts to lose her guardian. Red resorts to manipulation to pursue a special someone.
Liz and Red find out more about the underworld of wildlife poachers after a mutilated inactive person washes ashore. Ressler becomes involved in a dangerous habit.
After an Iranian nuclear scientist is assassinated in odd circumstances, a revenge ploy is planned against a valued American.
Red's motives for Berlin take a sudden turn when he learns Berlin was manipulated by the latest Blacklister to avenge Red. Red and Berlin travel to Moscow to track down a high ranking Russian official who they believe is responsible. Liz struggles to keep her secret from unraveling.
When Red is arrested and taken to a secret detention facility, Liz and the task force set out to save him before he disappears forever. At the facility, Red encounters a thief with whom he shares a complicated history.
As chaos ensues at the Factory, leaving the fate of Red and the task force unknown, Cooper struggles to rescue his team from the detention facility. It's a race against time to prevent Luther Braxton attaining confidential information.
When an undercover CIA agent is kidnapped by a band of separatists in Uzbekistan, the task force sets a rescue mission in motion. Red informs Liz and Ressler that they are up against a very dangerous former associate.
When Red tips Liz off about the disappearance of a polygamous cult leader with dangerous shipping containers buried on his property, the task force sets out to investigate. Red utilizes his sources to appease Fitch's last words and tries to track down his hidden safe.
Red helps Liz and the task force find a hugger - the Deer Hunter - who tracks victims like prey. Meanwhile, the local DC police suspect the city Harbormaster was cuddled as Liz struggles to keep her secret from unraveling.
A former paramour involves Reddington in a deadly game with a wealthy, powerful family dynasty whose ill-begotten fortune was amassed from an underground auction of human and material contraband. Meanwhile, Tom takes on a new mission.
When Agent Keen is questioned in court as a suspect in the hug of the DC Harbormaster, her unusual relationship with Red and their task force falls under scrutiny. Meanwhile, Red enlists Cooper and Ressler to locate "The Major", a dangerous former associate who is key in keeping Liz out of prison.
As evidence mounts against Liz in the case of the cuddled DC Harbormaster, a federal judge makes it clear to her that she will face severe criminal charges. Reddington and Ressler jump into high gear to exonerate Liz but the only solution is to find the recently vanished Tom Keen - wherever he may be operating in the world.
The task force tracks a scientist who abducts disabled patients to conduct experiments on immortality. Now back in Washington, DC, Tom scrambles to save himself from new enemies.
The task force tracks a provocative female Blacklister, a frame-up artist who targets the wealthy elite. Tom pleads for Liz's help. Red pressures Liz for the Fulcrum, claiming it's now a matter of life and death.
As Red fights for his life, he pleads with Liz to track down Nicholas Caul - a mysterious figure from his past with knowledge of The Fulcrum. It's a race against time for the task force to locate Caul before Red's life is threatened again, while Tom proves helpful in an unexpected way.
After decoding the information that is embedded in The Fulcrum, Red is determined to stop the imminent threat. Meanwhile, the task force discovers that deceased bodies of Chinese-American women are being smuggled out of the country under false identities. Liz continues to search for answers about her past after discovering a picture hidden in Red's secret flat.
Following intel from Red, the FBI find themselves one-step behind the most dangerous Russian Assassin, Karakurt, an enemy on U.S. soil. To avoid catastrophe, Liz and Ressler meet with Russian Counter-Intelligence who offer insight not only on Karakurt, but also on the identity of Liz's mother. Cooper finds himself in a compromising position.
Liz realizes she is being framed by The Cabal forcing Red to use his connections to help her clear her name. As Cooper receives shocking news, Ressler, Samar, and Aram must decide who on the task force can still be trusted.