Following Noel and Sue Radford and their children during the festive period, which might be the last one as a family of 22 with Daniel planning to move to Australia in the new year, but sibling rivalry leaves the clan at war with one another. Sue and Noel attempt to bring them back together with a variety of incentives including a surprise party at the bakery, a present reward chart (that goes horribly wrong), and team-building fun at the Christmas markets.

Millie's unborn child is severely distressed, and she's rushed to the hospital. And Katie, has gone missing. Full of jealousy, she packs her bags to follow boyfriend Connor to Zante.

Noel and Sue Radford make the biggest decision of their lives and decide to search for another house, but the older children soon realise there are more of them than there are rooms. So, who stays, and who goes? Meanwhile, Ellie is subjected to cruel online trolling during her 18th birthday celebrations, leading to Sue finding a way to boost her flailing confidence.

The Radfords are faced with devastating news from their closest friends the Walkers when their 16-year-old daughter Sophie's cancer returns and an expensive trip to America looks like her only chance for treatment. Noel and Sue rally the troops to raise life-saving funds, kicking off with an urgent video appeal to their half a million followers on social media.

Jake and Chloe are forced to face their relationship problems as they prepare to celebrate Mila's first birthday with a big party for family and friends at Radford HQ. Katie wants to squeeze an extra body into the home in the form of long-term boyfriend Connor - but can they pack him into an already bursting house?

Noel and Sue are locked in a battle of wills to control their brood and their disagreements have Max and his 24/7 gaming at their centre. Younger brother Casper tries to entice Max into the garden, while Sue arranges for a fun half-term getaway, which goes disastrously wrong when Max plays his parents against each other and tricks Noel into believing he can stay at home. Sue rushes to Millie's aid when one-year-old Chester is proving a handful for Millie.