LaDonna signs up for fifteen more minutes of fame but quickly realizes she doesn't have the clout she once had, so she turns to an unlikely source to help further her agenda, meanwhile Jharrell picks an inopportune time to speak his truth, and it may cost him dearly. Andre is eager to get back to medicine while everyone is eager to feel a bit of normalcy again. Shanice takes a step towards repairing her relationship with her daughter and Hayden and Mildred enjoy an impromptu celebration.
4400 overlooked, undervalued, or otherwise marginalized people who vanished without a trace over the last hundred years are all returned in an instant, having not aged a day and with no memory of what happened to them. As the government races to analyze the potential threat and contain the story, the 4400 themselves must grapple with the fact that they've been returned with a few… upgrades, and the increasing likelihood that they were all brought back now for a specific reason.