Kelly and Silver deal with news that their mother, Jackie, is suffering from breast cancer. Navid's world is shaken up when Adrianna tells him she needs time alone, but ends up turning to Teddy. Jen continues to use Naomi and convinces her to lend her money. Jasper rescues Annie from a bad date, leading the two to form a bond.
The series revolves around the three-generational Wilson family who have recently moved to Beverly Hills, California after the father Harrison Wilson accepts the position of being the principal of West Beverly Hills High School.