A medium approaches Danny and Baez claiming to know what happened to a woman who was found dead of an apparent suicide. Also, Jamie and Eddie help a woman who bought cheap insulin online that nearly killed her son; Frank goes against the wishes of the archbishop to take down a man he believes is laundering money from a charity; and Erin's ex-husband asks her for help with an assault and robbery case.
Frank Reagan is the New York Chief of Police and patriarch of the Reagan brood, which he heads as diplomatically as he does the force, even when dealing with the politics that plagued his unapologetically bold father, Henry, during his stint as Chief. A source of pride and concern for Frank is his eldest son Danny, a seasoned detective, family man and Iraqi War vet who on occasion uses dubious tactics to solve cases. The sole Reagan woman in the family, Erin, is a N.Y. Assistant D.A. and newly single parent, who also serves as the legal compass for her siblings and father. Jamie is the youngest Reagan, fresh out of Harvard Law and the family's "golden boy".
However, unable to deny the family tradition, Jamie decided to give up a lucrative future in law and is now a newly minted cop, a career change seemingly supported by his beautiful girlfriend, Sydney Davenport, a first year lawyer. Jamie's life takes an abrupt turn, however, when he's asked to become part of a clandestine police investigation even his father knows nothing about, and one that could impact the family's legacy.