Dr. Rhodes receives an alarming phone call that prompts him to rush out in the middle of an important surgery. Dr. Halstead comes to the aid of an FBI agent who is brought into the ER, but he suspects there is more to the story than he is being told. Dr. Manning and Dr. Choi find themselves on opposite sides of a major disagreement over doctor-patient confidentiality.
The newest installment of the compelling 'Chicago' franchise, an emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room, and through it all, familiar faces from the Chicago police and fire departments will intertwine as this third team of Chicago heroes hits the ground running.