In the wake of Joan's difficult breakup with Adam, God tells her to do some therapeutic cleaning, which ends up putting her in the middle of a scandal involving her guidance counselor...
As part of Joan's clean sweep, she returns everything Adam ever gave her, which only adds to the awkwardness between them. Meanwhile, when Joan returns some items to Mr. Tuchman that he loaned her, a jealous student with feelings for Tuchman vindictively tells the school authorities that Tuchman initiated intimate relationships with both her and Joan.
Also, Kevin considers getting a place of his own.
A drama about a typical family, the Girardis, facing atypical situations - not the least of which is their teenage daughter Joan's sudden, unexpected conversations with God in such random forms as a cute boy, Goth kid, little girl or the school lunch lady. Joan (Amber Tamblyn) must endeavour to balance the natural and supernatural elements of her life, often with little success. This is not the only major problem the family must face as her elder brother Kevin (Jason Ritter) was paralysed from the waist down in a car accident in 2002. As a result, her younger brother Luke (Michael Welch) often feels that his needs are being ignored.