Fearing a ghost and a curse, Úrsula and José Arcadio leave their town to establish a new home along a few others, braving a journey through tough terrain.

Aureliano has visions of a war, while José Arcadio Jr. meets a woman. José Arcadio's alchemy obsession pushes Ursula to find a way to support the family.

An odd girl brings a delirious sickness to Macondo. José Arcadio becomes fascinated by Melquiades' camera. Rebeca and Amaranta vie for Pietro's attention.

A new mayor and his family settle in Macondo. Aureliano experiences love for the first time, while a passing drives José Arcadio into madness.

Arcadio becomes the school's principal, and Pilar has significant news for Aureliano. Remedios fills the Buendía home with joy - until tragedy strikes.

José Arcadio Jr. returns, shocking everyone with his wild nature, specially Rebecca. Amid political unrest, Aureliano becomes a revolutionary leader.

Arcadio enforces liberal rule in Macondo, while Aureliano attempts to free a colonel from the conservatives. The looming threat of war finally arrives.

Years later, when Aureliano reveals his war plans for Macondo, a heartbroken Ursula comes to a shocking realization about her family.