The crew of Nathan James discovers that hospital ship USNS Solace was sent to sea to wait for Dr. Scott's cure. Captain Chandler sees an opportunity to add another ship to their fleet while Rachel is eager to find a lab better equipped to replicate the vaccine. When Solace fails to respond to radio communications, Chandler and his team board the ship... and come face-to-face with an unexpected enemy.
A global virus pandemic nearly obliterates the earth's population, forcing the crew of a naval destroyer to confront the reality of their new existence in a dangerous new world where they are among the only survivors. They must find a way to pull humanity from the brink of extinction.