Karen is finally forced to come to terms with her feelings for her presumed-dead husband when Jack surprisingly tells her he thinks she belongs with Stanley, not Malcolm. Karen is adamant that she will never forgive Stan and wants nothing to do with him--until Malcolm informs her that Stan has given her to him without a fight. Meanwhile, the new, charitable Will begins doting on the elderly Clyde and invites him to the Tenth Anniversary Game Night Spectacular, much to Grace's dislike. He is worried that he will end up like Clyde one day--a lonely old gay, but it turns out that the old man and Will don't have as much in common as originally thought.
The show takes place in New York City and focuses on Will Truman, a gay man and lawyer, and his best friend Grace Adler, a Jewish woman who runs her own interior design firm.
Also featured are their friends Karen Walker, a rich socialite, and Jack McFarland, a struggling actor/singer/dancer who also has had brief careers as an acting teacher, back-up dancer, cater-waiter, talk-show host and student nurse.