With no archrival to combat, Jack sets his sights on a new mission: write the most brilliant philosophy book ever and get out of Toledo for good. Stef and Mary forget a special day for Michele. Helen forgets to order routine maintenance for the copier causing mass hysteria at Whitlock.
When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job to his rival Miles Leonard, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement Biology teacher. As he comes crashing into Whitlock High School, Jack makes it absolutely clear he will not be teaching any biology.
Realizing he has a room full of honor roll students at his disposal, Jack decides instead to use the kids for his own benefit like getting revenge on Miles. Eager to prove that he is still king of the castle, Principal Durbin struggles to control the force of nature that is Jack Griffin.