A tornado puts the school on lockdown and Helen believes it's coming specifically for her; the kids pass the time by writing fan fiction, "shipping" various combinations of faculty members; Mary, Stef and Michelle devise a plan to escape the school.
When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job to his rival Miles Leonard, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement Biology teacher. As he comes crashing into Whitlock High School, Jack makes it absolutely clear he will not be teaching any biology.
Realizing he has a room full of honor roll students at his disposal, Jack decides instead to use the kids for his own benefit like getting revenge on Miles. Eager to prove that he is still king of the castle, Principal Durbin struggles to control the force of nature that is Jack Griffin.