As Wolf deals with a personal crisis that brings up dark corners from his past, the interns assist an MMA fighter exhibiting strange symptoms. Meanwhile, Pierce is visited by Bitsy, an Upper West Side housewife with a penchant for gossip, who gives her some shocking intel about a nearby influential surgeon.

A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General. Wolf clashes with Frederick over a personal matter.

Dr. Wolf and his team treat a young patient accused of a serious crime. Dana navigates unfamiliar territory in the romance department. Pierce returns to work.

Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.

When two patients arrive in critical condition, Dr. Wolf and Dr. Nichols must do whatever it takes to keep them alive.

Dr. Wolf is haunted by a ghost from his past. A patient arrives at Bronx General who appears to have risen from the dead.

A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.

Wolf treats a heroic firefighter who struggles to share his ALS diagnosis with his family.