Martin prepares to face his hearing, but despite having closed the practice, he finds all his patients are trying to make appointments. An American tourist who visited Portwenn previously returns to the town, hoping to research her family tree. However, she also has a medical issue, and comes to the troubled doctor seeking his advice. Louisa goes to see Chris to find out how serious the situation is, while the townsfolk take steps to show Martin how much he is appreciated. Sigourney Weaver reprises her guest role from the previous series.
Make an appointment with the brilliant but socially awkward and neurotic Doc Martin. When Martin develops an aversion to blood, he abandons his career as a celebrated London surgeon and becomes the only doctor in a sleepy small town where his tactless manner soon has the whole town in an uproar.