A mysterious illness takes hold of Piper, while Jo and Benny investigate a powerful tech mogul, Richard Kindred. As Piper's health deteriorates, Jo weighs accepting help from an unknown source. Meanwhile, Alex works to decipher a radio frequency code from Piper's plane crash, and Ed has a follow-up oncology appointment.
After Jo, a police chief, takes in a young child she finds near the site of a mysterious accident, she soon discovers the girl has no memory of what has happened or who she is. The investigation into the history that led up to the the accident - and questions as to how and why it happened - draws the woman into a conspiracy larger than she ever imagined, with the child's identity at the center of it.