After launching a deadly missile at Angelo, Lucious announces his new music project, Inferno, and puts everyone on notice - especially Cookie, who then vows to knock him off his throne for good. The two engage in an epic clash - fueled by a history of love, loyalty and betrayal. Meanwhile, Jamal befriends musician Tory Ash during his stay in rehab, Andre continues with his plan to take over EMPIRE, and Hakeem and Tiana battle Nessa for a spot in the music showcase.
Lucious Lyon is the king of hip-hop. An immensely talented artist, the CEO of Empire Entertainment and a former street thug, his reign has been unchallenged for years. But all that changes, when he learns he has a disease that is going to render him crippled and incapacitated in a matter of three years. The clock is ticking, and he must groom one of his three sons to take over his crowning achievement, without destroying his already fractured family.