The Lyons fear that the Dubois family is to blame for their latest family crisis, so when no one is willing to give up any information, Cookie takes matters into her own hands. Jamal and Lucious reach a breakthrough in a song on which they have been working, and Andre lashes out. Meanwhile, Cookie sets her eyes on a new plan for Empire in Vegas.
Lucious Lyon is the king of hip-hop. An immensely talented artist, the CEO of Empire Entertainment and a former street thug, his reign has been unchallenged for years. But all that changes, when he learns he has a disease that is going to render him crippled and incapacitated in a matter of three years. The clock is ticking, and he must groom one of his three sons to take over his crowning achievement, without destroying his already fractured family.