Zoe is blissfully happy when she sees how well Joel is adjusting to BlueBell, until, she learns the townspeople might have a different opinion of him. Wanting to make things better, Zoe volunteers herself and Joel to chaperone the Go Girl Tween Adventure Camp, but when Joel refuses to go along, she is left to fix the the town's perception on her own. After a rough start with Lynly, George is pleasantly surprised when he learns they work well together. Meanwhile, Lavon is desperate to be part of the Gazebos of Alabama calendar, but when a crucial flower mistake jeopardizes his plan, Lavon begs Lemon to help save the day.
Fast-talking New Yorker and brand new doctor Zoe Hart has it all figured out - after graduating top of her class from medical school, she'll follow in her father's footsteps and become a cardio-thoracic surgeon. But when her dreams fall apart, Zoe decides to accept an offer from a stranger, Dr. Harley Wilkes, to work with him at his small practice in Bluebell, Alabama. Zoe arrives in this small Gulf Coast town only to find that Harley has passed away and left his half of the medical practice to her in his will.
She quickly finds that Southern hospitality isn't always so hospitable - the other doctor in town, Brick Breeland, is less than pleased to be sharing the practice with this young outsider, and his daughter, Lemon, is a Southern belle whose sweet disposition turns sour when she meets Zoe. Zoe's only allies are the mayor, former football star Lavon Hayes, her bad-boy neighbor Wade Kinsella, and handsome lawyer George Tucker - who just happens to be Lemon's fiance. Zoe is out of her element and ready to pack her bags, but a surprise visit by her snobby New York mother leads to Zoe's decision to stay in Bluebell for a while, discovering small-town life and a side of herself she hadn't known was there.