Jane Villanueva is a driven young woman studying to become a teacher, nursing a dream to be a writer, and supporting herself with a job at a hot new Miami hotel. All the years of watching telenovelas with the two women who raised her - her sexy, young-at-heart mother, Xiomara and her still-devout grandmother, Alba - have given Jane a slightly unrealistic view of romance, but her wonderful fiancé, Michael, is supportive and even understands her decision to "save herself" until marriage. All of Jane's meticulous life plans are turned upside down, however, when she sees her doctor for a routine check-up and is accidentally artificially inseminated with a specimen meant for someone else. Now, Jane is faced with the most important decisions of her life - a life that has suddenly become as dramatic, complicated and unpredictable as the telenovelas she has always loved.
Jane struggles to keep her unexpected pregnancy from taking over her life, but with her mom Xiomara pressuring her to sue the doctor who accidently inseminated her, and her constant run-ins with the baby's biological father, Rafael, life is anything but normal. To top it off, Michael's jealousy about Jane and Rafael's past leads him to make an unexpected alliance with Petra. Meanwhile, Jane's own father, Rogelio, is insisting on meeting his daughter, but Xiomara wants to keep the secret from Jane a little while longer.
Jane considers making a life-changing decision about her and Michael's relationship. Alba is disappointed in Xo's handling of Rogelio, so Alba takes it into her own hands to stop Rogelio from trying to see Jane. Meanwhile, Jane continues to question whether Petra will be a fit mother, and her pursuit of the truth leads to an unexpected change in their relationship. Michael's on-going hug investigation leads to an unexpected discovery.
In addition to being overwhelmed with all the wedding planning, Jane begins to feel guilty about her emerging feelings towards Rafael and decides to tell Michael during their pre-wedding counseling. Elsewhere, Rafael and Petra are faced with someone from their past and neither are happy about it. Meanwhile, Rogelio learns about Jane's impending nuptials and pushes Xo to let him be part of his daughter's wedding.
Furious at her mother Xo, Jane decides she needs some space and moves in with her fiancée, Michael. However, living together isn't what she thought it would be and Jane has to rethink her plans. Jane makes an effort to get to know Rogelio, but when his nerves get the better of him, things don't go quite as planned. Meanwhile, Rafael and Petra continue to struggle with the state of their marriage, but Petra has another unusual plan up her sleeve.
Jane and Rogelio begin to grow closer until she meets his mean twin teenage stepdaughters, who are determined to make her life miserable. Rogelio insists Xo uses his band for her big performance at the Mirabella Hotel, but the band is not what she was expecting. Elsewhere, Rafael finds himself arrested after Petra files a complaint against him. Meanwhile, Jane is conflicted about the direction of her relationship with Michael and what will be the best choice for her.
Jane decides the best thing for her is to stay away from Rafael, but when her friends insist on taking her to the hot new club that he owns, she finds it hard to avoid him. Elsewhere, Xo and Rogelio each have dinner plans, so Rogelio suggests they have a double date, but the evening doesn't work out as planned. Meanwhile, Petra is once again scheming to make Rafael's life more difficult.
Jane and Rafael both reveal shocking secrets to each other. Xo is excited when a music producer, Elliot, contacts her to record a demo, but little does she know that Rogelio had a hand in making it happen. Meanwhile, Michael is close to a big break in his case, and Petra finds new was to make Rafael's life difficult.
Jane and Rafael are both concerned about Petra's true intentions with the baby, especially after they discover one of her shocking secrets. Rogelio is nominated again for a Best Actor award and invites Jane, Alba and Xo to attend the show with him. Xo is about to give up on her dreams, but when she meets her ultimate idol, Paulina Rubio, she has a change of heart. Meanwhile, Michael unveils a huge clue in his ongoing investigation.
As a hurricane rips through Miami, Jane is forced to stay at the Marbella, but the storm soon becomes the least of her concerns. When Rogelio hears about Alba's condition, he rushes to Xo's side at the hospital to comfort her. Rafael is reinstated as boss, but he is soon faced with a difficult decision regarding layoffs at the hotel. Meanwhile, Michael helps Alba, but does his best to keep it a secret.
When the nuns surprise Jane by offering her a permanent teaching position, she's excited, but things become complicated when Rogelio offers Jane a writing internship at his telenovela. Alba encourages Xo to keep the promise she made to God about Rogelio. Meanwhile, Michael is convinced of Rafael's involvement with the mysterious Sin Rostro and disobeys his boss' direct order to leave Rafael alone.
Jane gets a big break in her career, but it all seems too good to be true, especially when it involves Rogelio. Rafael is stressed about Sin Rostro's connection to the hotel and begins to fear for his family's safety. Meanwhile, Petra's past is quickly catching up with her and she is disheartened when she learns the truth about someone very close to her.
Jane and Rafael are excited to find out the sex of the baby, but a medical issue means Jane might miss her graduation. Xo notices that something is going on with her mother, Alba, but Alba is too embarrassed to talk about it. Meanwhile, Michael thinks he has finally figured out who Sin Rostro is, but he must try to capture him before he slips away.
Michael is convinced that Rafael is helping to hide his father, and puts the thought into Jane's head as well, making her grow suspicious of Rafael's recent actions. Elsewhere, Jane forces Xo and Rogelio to reveal how they really feel about each other, but neither is prepared for what the other has to say. Petra finds a new way to torture Rafael that even he could not have imagined. Meanwhile, Jane's friends want to throw her a baby shower, but it brings up some serious questions about her and Rafael's future.
When Jane and Rafael receive news about their baby's health, they revisit moving in together which prompts a surprise from Rafael. Alba gives Jane and Xo relationship advice that they both take to heart, but which leads them to unexpected friction with Rafael and Rogelio. Meanwhile, Petra finds herself with an unexpected ally. Michael tells Jane that her favorite literary idol is staying at the Marbella and Jane is determined to get her own book into her hands.
Jane is feeling distant from Rafael so she focuses on her writing instead, but is stuck with a case of writers block. When Jane runs into Michael he mentions a romance writing workshop, and she thinks she has found the solution. Petra has a solution to finding a musical performer for the Mirabella's Calle Ocho celebration, but it forces Rafael to ask Rogelio for help. Rogelio is struggling with his new character as a detective, so he gets the brilliant idea to shadow Michael for real cop experience. Meanwhile, Xo has made a decision about her life with Rogelio which causes a rift between her and Alba.
When a crisis with the hotel overwhelms Rafael, Jane becomes concerned that he might not be as hands-on in fatherhood as she expected. Alba is having a difficult time with Xo's living situation which causes a strain between them. Michael helps Rogelio with his relationship with Xo, and in return Rogelio helps Michael come to a realization about Jane. Meanwhile, Petra discovers a big secret that leaves her unsettled.
Jane unintentionally ruins Rafael's chances of getting the hotel's liquor license back, but her attempt to help fix it means missing the Villanueva's Easter festivities. Rafael gets information about his birth mother from the private detective he has hired, but doesn't like what he hears. Rogelio's mother, Sofia, comes for a visit but she and Xo do not have the best history. Alba takes a big step in the romance arena, but is shocked when she learns what Edward does for a living. Meanwhile, Petra becomes more convinced about the secret she thinks she has stumbled upon and enlists Michael's help to get confirmation.
Jane is desperate to fix things with Rafael and suggests working on a way to help them move past their problems. Xo has been keeping a secret from Rogelio, but when she finally comes clean to him, Rogelio's reaction surprises her. Alba has a flashback of who pushed her down the stairs. Still dealing with the Sin Rostro aftermath, Michael makes an upsetting discovery about who was involved all along. Meanwhile, Petra finds herself in a dire situation leaving her to save herself.
Jane is determined to do what's best for the baby, especially after she and Rafael learn that the baby is breech. Xo continues to try to apologize to Rogelio, but faces an uphill battle. Rogelio is offered a big career opportunity that could bring him back to his glory days. Meanwhile, Alba shares what happened the night of her accident and Jane turns to Michael for help in catching Petra in a lie.
Jane is nervous to attend her five year high school reunion because she feels her life is not what she expected it to be. Rafael confides in Petra about Jane's custody request, making Petra think she can fix the problem and become the hero. Xo is confused about Rogelio's reaction during their show rehearsal until she learns the real reason behind it. Meanwhile, Jane agrees to attend Michael's commendation ceremony, but she has a few ground rules.
After having false labor, Jane insists that Xo and Rogelio go to Las Vegas to perform their show, but once they are gone the labor turns very real. Xo does everything she can to get back to help Jane, but ends up making Rogelio feel like he's not part of the family. The truth about Michael and Rafael's feelings for each other, and Jane, are put aside to help make Jane's labor easier. With the good news on the birth of Jane's baby, Alba is excited to tell her special friend. Meanwhile, Petra learns some very important information that concerns Rafael, leaving her to decide if she should tell him.