Jane thinks she is finally ready to make a decision about her love life. Alba has taken the proper steps to become a citizen, but Xo's past might make it more difficult than anyone was expecting. Rogelio learns that his nemesis, Britney Spears, is at the Marbella Hotel and he is determined to confront her about their past. Michael is so caught up in his ongoing feud with Rafael that he ends up in big trouble at work. Meanwhile, Petra gets an offer from her ex Milos she just can't refuse.
Set in Miami, the series details the surprising and unforeseen events that take place in the life of Jane Villanueva, a hard-working, religious young Latina woman whose family tradition and a vow to save her virginity until her marriage to a detective is shattered when a doctor accidentally artificially inseminates her by mistake during a checkup. And to make matters worse, the biological donor is a married man, a former playboy and cancer survivor who is not only the new owner of the hotel where Jane works, but was also her former teenage crush.