Jane's burgeoning relationship with Adam helps bring out her fun side and reminds her that she isn't just a mom. However, when Adam gets a job opportunity, he asks for Jane's opinion on if he should stay or go. Rogelio is facing issues with his co-star at work and things are about to get even worse for him. Xo is helping to take care of Darci to prove that Rogelio is committed to being a father to the baby. Meanwhile, Petra and Rafael are working together to try and buy back the hotel, but are running into trouble, causing tension between them.
Set in Miami, the series details the surprising and unforeseen events that take place in the life of Jane Villanueva, a hard-working, religious young Latina woman whose family tradition and a vow to save her virginity until her marriage to a detective is shattered when a doctor accidentally artificially inseminates her by mistake during a checkup. And to make matters worse, the biological donor is a married man, a former playboy and cancer survivor who is not only the new owner of the hotel where Jane works, but was also her former teenage crush.