After Pride's assistant, Ginny Young, escapes from a kidnapper, the NCIS team uncovers evidence of a suspect who is harvesting organs from multiple victims. Also, Pride turns to his friend, Commander Calvin Atkins, M.D., for medical and spiritual guidance as he struggles with the ramifications of his recent brush with death.
The local NCIS field office investigates criminal cases affecting military personnel in the Big Easy, a city known for its music, entertainment and decadence. Leading the team is Special Agent Dwayne Pride, aka 'King', a native of NOLA who is driven by his need to do what is right. Working with Pride is Special Agent Christopher LaSalle, who plays hard but works harder; and Special Agent Meredith 'Merri' Brody, a charismatic and tough interrogator who transferred from the Great Lakes office in search of a fresh start. Supporting them is coroner Dr. Loretta Wade, who is as eccentric as she is smart. This colorful city that harbors a dark side is a magnet for service personnel on leave, and when over-indulgence is followed by trouble, Pride's team is at its best.