Rugby player Luke from Hull has Tourette's syndrome and finds it hard to control his physical and vocal tics. With a job as a chef, a degree in science and health, and a great set of friends, Luke believes finding a girlfriend is the final piece of the puzzle. Bookseller Sam from Cambridgeshire longs for the romance he reads about in novels. Sam has Asperger's. He is gay and finds the scene intimidating, but is ready to put himself out there. Photography graduate Becky from north London is a self-confessed romantic. Becky has scoliosis, a genetic condition that causes a curvature of the spine. Becky has never had a boyfriend, but is determined to do something about it.
Alex has been single since breaking up with his girlfriend a year and a half ago. Proud owner of a new sports car, the 24-year-old is ready to re-join the dating scene. But Alex, who's autistic, struggles to talk to new people, especially girls. He's hoping his date with Ellie, at the zoo, will accelerate him back into the fast lane of dating. Identical twin Jason is an airplane buff. The 25-year-old, who has Asperger's, longs to meet his own co-pilot, but has a tendency to rush into relationships too quickly. In a new career move, rugby player Tom, from Bridgend, has taken to the catwalk. But while his model looks mean he's not short of attention, the 28-year-old has Tourette's and Asperger's, which makes him shy when speaking to girls.