Yorick, Agent 355 and Dr. Mann hit a snag on their way to San Francisco. As the search for 355 heats up, Jennifer clashes with former cabinet secretary Regina Oliver, who has her eyes on the presidency. Hero is seduced by a charismatic leader, Roxanne, as Sam and Nora grapple with their place in a dangerous group of survivors.
In a post-apocalyptic world a mysterious cataclysmic event simultaneously killed every mammal with a Y chromosome but for one man, Yorick Brown, and his pet monkey Ampersand. The series follows Yorick as he traverses the new world, as its survivors struggle with their losses and attempt to restore world society - led by Yorick's mother, who is the new U.S. President Jennifer Brown.
Y: The Last Man - Weird Al is Dead Synopsis and Schedule