On the heels of ViCAP uncovering the secrets behind the River Murders case, Clarice is imprisoned in an abandoned animal testing facility where she finds trafficked women being held captive. As Clarice attempts to break from her captors and rescue all the women, ViCAP and Ardelia team up to locate her.
FBI Agent Clarice Starling returns to the field in 1993, one year after the events of The Silence of the Lambs. Brilliant and vulnerable, Clarice's bravery gives her an inner light that draws monsters and madmen to her. However, her complex psychological makeup that comes from a challenging childhood empowers her to begin to find her voice while working in a man's world, as well as escape the family secrets that have haunted her throughout her life.