The Struckers, minus Andy, begin to rebuild their broken trust, while Thunderbird, Blink and Eclipse visit Wire, hoping to convince him to help again. But when they get there, they learn that something terrible has happened from Wire's brother, Graph. The team discovers that the Inner Circle is on the way to raid a mutant detention facility, so they make moves to try to intercept them. Meanwhile, Jace is contacted by a member of the Purifiers.
The lives of an ordinary suburban family change course forever when they discover their children have developed mutant powers. When the threat of a hostile government forces the family to go on the run to protect themselves, they join the ranks of an underground network of mutants. Together, the group fight to survive in a world where fear and misunderstanding put them at constant risk.