As Caitlin and Thunderbird struggle to save the life of a mutant injured in the Inner Circle's chaotic liberation of a psychiatric hospital, they discover clues to the identity of the powerful mutant Polaris and Andy were sent to retrieve. Meanwhile, as Jace joins up with the Purifiers to chase down the escaped mutants, he comes dangerously close to colliding once again with the Mutant Underground.
The lives of an ordinary suburban family change course forever when they discover their children have developed mutant powers. When the threat of a hostile government forces the family to go on the run to protect themselves, they join the ranks of an underground network of mutants. Together, the group fight to survive in a world where fear and misunderstanding put them at constant risk.