In light of the Sokovia Accords, and with Hydra obliterated, S.H.I.E.L.D. has been legitimatized again and no longer needs to operate in the shadows. Since the world presumes that Coulson is dead, the organization needed a new Director to be the face of the organization. Coulson finds himself back in the role as an agent and teamed with Mack, and together they are tasked with tracking down and confirming the presence of Enhanced people, aka Inhumans. Agent May is tasked with training specialist strike teams, and Fitz and Simmons have taken a big step forward in their relationship.
Season 4 Episode 1 of Marvel's Agents of S.H.I.E.L.D. was watched by 3,440,000 viewers, resulting in a 1.10 rating in the 18-49 demographic.
After surviving events on the Helicarrier, S.H.I.E.L.D. Agent Phil Coulson puts together a small team of S.H.I.E.L.D. agents to handle strange new cases. They investigate Project Centipede, eventually uncovering that Centipede is backed by the organization Hydra, which has infiltrated S.H.I.E.L.D.
Following the destruction of S.H.I.E.L.D., Coulson and his team look to restore trust from the government and public while dealing with Hydra and the newly revealed Inhumans, people who possess special abilities. Coulson's work is further complicated by the appearance of another faction of S.H.I.E.L.D. agents who do not trust his leadership.
Coulson begins a secret mission to assemble a team of Inhumans to deal with new threats to the world, while Hydra returns its ancient banished Inhuman leader to Earth.