Will is troubled with a moral decision when his former teacher, Dr. Bella Rowan, is faced with a life-threating disease. Dr. Rhodes and Dr. Bardovi get involved in a sensitive situation when Rhodes disagrees with the father of a young patient regarding a risky procedure. Dr. Charles and Sarah handle an unusual case with a pilot that causes Sarah to have memories of Jason Wheeler's suicide. Maggie takes an aggressive approach to training a new nurse.
The newest installment of the compelling 'Chicago' franchise, an emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room, and through it all, familiar faces from the Chicago police and fire departments will intertwine as this third team of Chicago heroes hits the ground running.