ER follows the medical personnel and patients in the emergency room of Chicago's fictional County General Hospital.
As the doctors and nurses of County's ER confront the daily challenges of a busy urban hospital, including overcrowded waiting rooms, staffing shortages, and the impact of life-and-death decisions. While they teach the next generation of doctors, the each must tackle demands of their personal lives, at times unsuccessfully.
The staff is led by Chief of Emergency Medicine Dr. Luka Kovac, a gifted teacher who came to Chicago from Croatia following the tragic death of his wife and children, but now finds his life on an upswing, and Dr. Kerry Weaver, County's Chief of Staff, a compassionate doctor and uncompromising administrator whose rigid style has isolated her from the medical staff. The ER is staffed by fourth-year resident Dr. Gregory Pratt, who puts patients before procedure, yet fears the responsibility now thrust upon him, feisty nurse Samantha Taggart a tough single mother attempting to balance her difficult personal issues with her demanding professional life, and Scott Grimes as the less than capable Chief Resident Dr. Archie Morris, along with a trio of second year residents: Dr. Abby Lockhart a former ER nurse turned doctor, building a new career and a new life that has taken a sudden and unexpected turn, Dr. Neela Rasgotra recently married and finding her role in the ER after a long period of uncertainty, and Dr. Ray Barnett who must make the choice between his career as a doctor and the rock band in which he plays. Featured this season as recurring characters are John Leguizamo as the innovative, and problematic, Dr. Victor Clemente, Kristen Johnston as demanding Nurse Manager Eve Peyton, and Leland Orser as the ER's highly individual surgical attending, Dr. Lucien Dubenko.