A case turns personal for Conrad when the donor recipient of Nic's heart is admitted to the ER. Bell is faced with a devastating diagnosis that causes him to make a heartbreaking decision. Meanwhile, the Raptor asks Devon to include his ailing mother in his clinical trial, causing Devon to face a major dilemma.
Conrad Hawkins is one of Chastain Park Memorial Hospital's best doctors. Charming and arrogant, Conrad likes to take an unconventional approach whenever possible and believes it's his personal duty to shatter the romantic illusions of the first-year residents. Dr. Devon Pravesh is an innocent idealist who leans on his finely tuned moral compass, but with Conrad's help, he begins to realize that the practice of medicine is a business, like any other, with less-than-angelic patients and fallible doctors. Lives may be saved or lost, but expectations will always be shattered.