Jane is having a hard time dealing with Rafael avoiding her, so when an issue with Mateo comes up she uses it to get some face time. Rogelio turns to Jane for help when he learns his pilot is in trouble. Alba and Jorge enlist Xo's help to study for their upcoming immigration test. Meanwhile, Petra finally gets to the bottom of who has been terrorizing her.
Set in Miami, the series details the surprising and unforeseen events that take place in the life of Jane Villanueva, a hard-working, religious young Latina woman whose family tradition and a vow to save her virginity until her marriage to a detective is shattered when a doctor accidentally artificially inseminates her by mistake during a checkup. And to make matters worse, the biological donor is a married man, a former playboy and cancer survivor who is not only the new owner of the hotel where Jane works, but was also her former teenage crush.