On the way to the next town, Ash and friends decide to stop and take a break. Dawn heads to a river to fill up her canteen, but is attacked by a wild Aggron and falls into the river. She manages to get out of the river far down stream, and is now lost from Ash and Brock. Aggron returns and after calling out Mamoswine, it is badly hurt. Now, Dawn must take care of Mamoswine by herself, and hide from Team Rocket and Aggron at the same time.
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.