Ash and friends have delivered the GS Ball safely to Kurt and are heading to the Azalea Town Gym for the next badge. Misty thinks Ash will have a tough time with without Charizard but Ash is confident that Cyndaquil has the firepower he needs.The Azalea Gym is a large dome with a forest-like environment inside. Misty becomes nervous, then a Caterpie drops down in front of her and she freaks. A boy standing up on a tree branch says that this is in fact the Gym and that bug Pokemon are the best. Misty isn't thrilled. Ash introduces himself and the boy says he's Bugsy, the Gym leader.
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.