Baz goes into labour as Charlie realises how difficult parenting can be from a patient as Mike is back in Holby on a 6 month contract.
Sam Colloby arrives at Holby for an interview for a job as a nurse as Kate isn't happy about a doctor using her husband to teach medical students.
Sam has his first day at Holby as a nurse whilst the nurses get a new uniform as Jude gets a surprise when her ex boyfriend arrives as a patient.
After winning money on the pools, Sam comes to the help of a two people from Glasgow as an old lady makes a shocking discovery about her husband.
Gloria finds herself made homeless after a fling with her landlord as the team have to save casualties from a swimming pool filled with chemicals.
Kate's daughter disagrees with her about keeping Trevor in his current condition as a grenade blows up in an allotment.
A father takes revenge on the man who supplied his daughter with drugs as Josh struggles to save the life of a girl injured in the middle of nowhere.
A pilot from the Royal Air Force struggles to cope after a crash which killed a friend as Richard tries to come to terms with his MS.
The team fight to save the lives of two girls trapped in a caravan crash as Kate and her children have to decide whether to let Trevor be treated or not.
It is Mike's last day in Holby before he returns to Africa as Trevor's condition continues to get worse.
Mike's replacement Jack Hathaway starts work at Holby and sets out to impress his staff as Baz has to deal with two underage girls working in a factory.
A young girl seeking medical help for her mother ends up being attacked by a dog as Baz finds herself upset over the death of a baby.
Discovering that she is pregnant, Jude is keen to have an abortion as soon as possible as the team deal with a drugs mule and a corrupt police officer.
Jude prepares to tell Matt that she is pregnant but Matt is considering a job in Crete as a cleric loses faith after his niece dies after being hit by a drunk driver.
Jude's pregnancy keeps her occupied making her doubtful about attending the party as the team deal with a stroke victim who ends up suffering another stroke.
Jude comes to a decision and decides to have an abortion which Matt provides support as a sex offender returns home only to face the victim's family.
Baz gets a shock when Liz and Penny bring in baby Louis into hospital as the team deal with a boy brought in by air ambulance after falling into the water.
Charlie finds himself feeling the pressure whilst dealing with a difficult patient as Louis is found to be in perfect health as the team deal with a pair of twins suffering the same problems.
As Jude goes to the clinic for an abortion, Charlie faces an investigation regarding sexual assualt.
The staff are shocked when Josh gets the worst call, a fire at his home that left his wife and son dead, his daughter fighting for life.
It is a busy shift at A&E as Josh comes in after the death of his entire family as Matt prepares to leave Holby.
A mugging brings a shy woman and the man she admires together and one of Richard's old flames turns up. It's a sad night in A & E, as Matt has had enough of attending the sick and needy from behind the reception desk and is off to serve the hot and thirsty in his brother's bar in sunny Crete. His leaving party goes awry but can he really leave Jude behind?
The new mural is unveiled but Jayne isn't there after a car crash as Josh deals with the fact his family have died.
The team battle on to save Jude's life after she has been embraced at Matt races back from Crete as the police hunt for the main suspect.