It is a busy shift for the staff as they try to treat a baby but the mother doesn't speak English but a fire at a school makes the shift even busier.
The team continue the race to save casualties from the school fire but Mark has also been injured and in a critical condition after a car crash.
Two youths attempt a robbery at on shop which fails leaving one of them injured as the team need a replacement for Mark who is still seriously injured.
Duffy returns to work at Holby in the role of an agency nurse as the team deal with a woman who has been locked in a room.
The team battle to save the life of a mother injured after saving a girl from being run over as Eve tries to help a homeless girl open up.
Mark is back at working following the car crash as Duffy is revealed to be considering accepting the job offer.
Sunny tasks Josh with putting some money on a horse for him but emergency call outs delay this task as Max gets a call about his drug addict son Frank.
It is a busy shift but Sean is acting strangely after the events of the previous week as a group of youths including Frank plan a robbery.
Charlie is driving to work when a man gets his attention as his wife need help as Adam informs Sam that he is HIV+.
Chloe is out for the day with Josh and Penny on the ambulance as a cross country run leaves a young boy in hospital.
It is a busy shift as the team have to deal with a group of protesters trying to stop trees from being cut as Eve is met with resistance regarding her 5 week holiday.
Sean is nervous as he faces the coroner over the death of a patient as his colleagues wish him luck as the team treat their patients including a young girl who has hit her head badly.
The team find themselves puzzled about a man who collapses in reception without a pulse before coming back to life as Sean is worried about facing legal action.
The team have a tough day as they deal with a prisoner who been brought in after an insulin overdose as Sunny goes with Amy to her ante-natal class.
A young boy in a care home runs away after being teased about wetting the bed as he meets another homeless boy who is eventually beaten up.
Penny and Josh are driving a patient back to Holby when a car ends up running a red light causing a crash as Duffy learns that Frank has run of with stolen jewellery.
A mother leaves her baby alone whilst she pops down the pub but ends up staying longer than planned as the staff get ready for the Christmas party.
Sunny can't help but keep going on about how he helped delivered Amy's baby as Mark is preparing to leave and go train to be a doctor as Josh is threatened over the money he owes.
Trouble escalates on a rough estate after a teenage lad is shot which soon escalates to outside the police station as Eve's friend Marius is found to have Crohn's disease.
A letter received by Sean by mistake reveals that Eve and Marius are married as Penny tries to get Josh to seek help over his gambling problem.
Max learns that the hospital could be closed down to form a major department over at St. Thomas' as a football sees a player having a heart attack after scoring a penalty shot.
Chloe is concerned that Tina is going to find out what happened with her and Sean as the departments complaint log is found to be full.
Josh and Penny are at the scene of a car crash when a fireman slips and injures himself as a mother leaves her baby with her adopted mum to visit her birth mum.
Josh and Penny are treating two patients at a derelict building only to find themselves trapped as when the floor collapses as George's research is going too slow for Max's liking.
Sean is in need of support with the approaching court case and ends up snapping at Tina as George tells Duffy she is thinking about applying for another job.
Thinks between Eve and Marius are awkward as the trust tries one last attempt at an out-of-court settlement as George has got herself a job interview at Broadway General.
George is on her way home after her shift but a stop at the bank finds herself caught up in a bank raid as Chloe is a bit tight whenever pregnancy is mentioned.
Following the bank raid, Josh and George find themselves being held hostage in the woods as Eve tells Charlie and Duffy Marius has returned to Romania.