Chloe's day is thrown into chaos when Evan is attacked, and with his life on the line, he asks her a surprising question. Dominic is put under pressure when a surprise visitor arrives at Holby looking for Lofty. Wanting to keep his marriage intact, Dominic is forced to make a difficult decision. After a night of partying together, Serena and Fleur Fanshawe are thrown together to help a patient on AAU.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital